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The Rigakubu News

Disclaimer: machine translated by DeepL which may contain errors.

Introduction to DNA origami

Masami Hagiya (Professor, Department of Information Science)


Ikubuki Kawamata, Yuki Suzuki, Satoshi Murata
Introduction to DNA orig ami
Ohmsha (2021)
ISBN 978-4-274-22713-4

DNA computing is a research field that aims to realize information processing by molecular reactions centered on DNA and, conversely, to implement molecular systems by utilizing information processing technology. DNA nanotechnology, which is a technological field that implements nanostructures and molecular robots using DNA, has emerged from this field. In particular, DNA origami introduced in this book is a milestone in DNA nanotechnology.

Although the concept and elemental technology of DNA origami are very "computer-scientific," the inventor of this technology, Rozmundo Rozmundo of the California Institute of Technology (Caltech), has actually invented this technology. Professor Paul W. K. Rothemund of the California Institute of Technology, who actually invented this technology, is a computer scientist in the field of DNA computing, and the author of this book, Assistant Professor Kawamata Research Student of Tohoku University, graduated from the Graduate School of Information Science in the Faculty of Science of Tohoku University and received his degree in the author's laboratory. He is also a computer scientist who graduated from the Department of Information Science, Faculty of Science, Tohoku University, and obtained his degree in the author's laboratory. After obtaining his degree, he has been active in the field of DNA computing.

This book not only describes in detail how to create nanostructures using DNA molecules, including software and experimental techniques, but also explains the basics of polymer chemistry and thermodynamics.

DNA computing can be positioned as a part of the larger field of "natural computation," which explores the relationship between various natural phenomena and information processing, not limited to molecular reactions. The author has been teaching a course on "Natural Computation" in the Faculty of Science until this year, but unfortunately this course will be terminated with the author's retirement at the end of March. In this lecture, DNA origami was also introduced, and I hope you will refer to this book in the future.

Published in Faculty of Science News March 2022

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