UESONO Yukifumi

UESONO Yukifumi
Assistant Professor, Research Associate
Department of Biological Sciences (Plant Science), Department of Biological Sciences (UG), Department of Biological Sciences (GR), Graduate School of Science
TEL +81-3-5841-4467  | 24467(ext.)
Room 25, Faculty of Science Bldg.2, BF

Research Field

Molecular genetics

Research Subject

Stress responses of yeast

Current Research

Cells respond and adapt to various extracellular changes. Environmental stresses, such as high osmolarity and acute glucose deprivation, rapidly and transiently shut down translation initiation and actin polarization in the yeast Saccharomyces cerevisiae. The biological significance of transient shutdown is considered to facilitate the spatial rearrangement of gene expression in response to environmental stress. Certain clinical drugs, such as local anesthetics and antipsychotic phenothiazines, and cationic surfactants also cause shutdowns similar to those triggered by the environmental stresses. The aim of my study is to elucidate mechanism of the shutdowns elicited by the stresses and the drugs.


yeast, osmotic stress, glucose deprivation, actin, translation initiation