ASAI Kiyoshi

ASAI Kiyoshi
Department of Bioinformatics and Systems Biology, Faculty of Science/ Department of Computational Biology, Department of Bioinformatics and Systems Biology (UG), Graduate School of Frontier Sciences
TEL +81-4-7136-3986 | 63986(ext.)
Room 360, Kashiwa Research Complex (Kashiwa Campus)

Research Field

Genome Information Analysis, Comparative Genomics<br>
RNA Informatics

Research Subject

Information Analysis of non-coding RNAs, Algorithms for RNA sequences considering their secondary structures, Comparative Genomics, Genome Annotation

Current Research

The target of our research is to clarify the "meaning" of the Genome. Genome sequences include various types of information, not only the amino-acid sequences of proteins, but their regulations, non-coding RNAs, and every history of evolution in our ancestors. We analyze DNA/RNA/protein sequences, their regulations, their functions, their structures, their interactions and their evolution using various types of mathematical models, which usually include statistics. Our favorites are stochastic models, machine learning theory, and dynamic programming. We have been developing software for the analysis of DNA/RNA sequences, including gene finding, structural alignment of RNA sequences, and secondary structure prediction of RNA sequences. We are one of the core members of bioinformatics in Functional RNA Project of NEDO. Asai Lab is located in Kashiwa Campus of University of Tokyo and Computational Biology Research Center (CBRC) of AIST in Tokyo Waterfront. Currently most of the students are studying at CBRC.


Sequence Analyais, Dynamic Programming, Stochastic Models, RNA Secondary Structures