| yamato.yoshida@bs.s.u-tokyo.ac.jp | |
| TEL | +81-3-5841-4471 |
| Room | Faculty of Science Bldg. 2, Rm#02 |
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Research Field
Organelle biology, Quantitative biology, Multi-omics
Research Subject
Decoding division mechanisms of organelles
Current Research
Chloroplasts (plastids) and mitochondria power a great deal of living organisms. Consistent with their endosymbiotic origin, plastids and mitochondria maintain themselves by binary division. Chloroplast division is carried out by a ring complex called the plastid-division (PD) machinery; the PD machinery has an inner ring (FtsZ ring) and an outer ring (PD ring) across the plastid membranes. Although many studies have examined plastid division, much about the components and molecular mechanisms of the PD machinery, as well as any parallels with the mitochondrial-division (MD) machinery, remain to be discovered. Therefore, the principal aim of our research is to elucidate the conserved mechanisms of plastid and mitochondrial division from primitive eukaryotes to higher plants and animals.
References:
1) Yoshida, Y. et al (2006) Science 313, 1435-1438.
2) Yoshida, Y. et al (2010) Science 329, 949-953.
3) Yoshida, Y., Mogi, Y., Allan, D. TerBush and Osteryoung, K. W. (2016) Nature Plants 2, 16095.
4) Yoshida, Y. et al (2017) Proc. Natl. Acad. Sci. USA 114, 13284–13289.
5) Yoshida, Y. (2018). J. Plant Res. 131, 727-734.
6) Yoshida, Y. and Mogi, Y. (2019) Microscopy 68, 45-56.
Keywords
Plastid division machinery, Mitochondrial division machinery, primitive eukaryote, multi-omics, single molecule microscopy