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KAYA Motoshi

KAYA Motoshi
Assistant Professor
Department of Physics (UG), Department of Physics (GR), Graduate School of Science
E-mail kaya@g.ecc.u-tokyo.ac.jp
TEL +81-3-5841-7646 | 27646(ext.)
Room 918, Faculty of Science Bldg.1, 9F
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Research Field

Biophysics, Biomechanics

Research Subject

Integration of function of multiple motor protein molecules

Current Research

In order to gain an insight into the functional mechanism of single / multiple motor protein molecules, I have been developing the fluorescence imaging and optical trapping system with a nanometer / piconewton accuracy. I focus particulaly on skeletal muscle proteins, myosins and actins.
In muscle cell culture, the dynamics of proteins and intracellular organelles are measured by in-cell imaging to understand the mechanisms of muscle cell fusion and sarcomere formation. I also focus on the extraction of features of cell morphology and kinetics using machine learning.

Keywords

molecular motor, single molecule measurement, myosin, actin, muscle, optical tweezers, fluorescence imaging